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What is MolDX and When Do I Need a Z-Code?

What is MolDX and When Do I Need a Z-Code?

by Alex Mitchell | Mar 19, 2026 | Clinical Laboratory, Industry Insights, Revenue Cycle Management, Denial Management, Payer Audits & Alerts

00:00 1X   Laboratories performing infectious disease testing and billing Medicare Part B within a MolDX jurisdiction are subject to a new Local Coverage Determination (LCD) that stands to significantly impact reimbursement for these services. Labs in the...
How Clinical Labs Can Improve Payer Network Access and Leverage

How Clinical Labs Can Improve Payer Network Access and Leverage

by Alex Mitchell | Jan 7, 2026 | Industry Insights, Revenue Cycle Management, Denial Management

00:00 1X   For most clinical laboratories looking to improve their payer network, reimbursement challenges aren’t an abstract business concern; they’re existential. For independent and small- to mid-sized reference labs/POLs, one reality remains consistent:...
Molecular Test Reimbursement: MolDX, Z-Codes & Payer Reform

Molecular Test Reimbursement: MolDX, Z-Codes & Payer Reform

by Alex Mitchell | Dec 2, 2025 | Industry Insights, Revenue Cycle Management, Billing & CPT Codes, Denial Management

00:00 1X   If you work in a clinical or molecular lab, you’re living this tension every day: advancements in testing keep moving forward, but reimbursement rules lag months or even years behind. New molecular tests, infectious disease diagnostics, and proprietary...
Balancing Compliance, Risk, and Revenue in Toxicology Testing

Balancing Compliance, Risk, and Revenue in Toxicology Testing

by Alex Mitchell | Nov 11, 2025 | Payer Audits & Alerts, Clinical Laboratory, Industry Insights, Tips for New Lab Owners, Denial Management

00:00 1X   For many labs, toxicology has long been a top target for payer audits. Reimbursement cuts and stricter “medical necessity” interpretations are raising denials, claw-backs, and scrutiny, especially around frequency of testing and documentation quality....
Understanding and Navigating Medicare MUE, PTP Edits

Understanding and Navigating Medicare MUE, PTP Edits

by Alex Mitchell | Sep 25, 2025 | Revenue Cycle Management, Pathology Management, Billing & CPT Codes, Denial Management, Industry Insights

The Medicare National Correct Coding Initiative (NCCI) (also known as CCI) was installed to promote national correct coding methodologies and to control improper coding leading to payment. NCCI Procedure-to-Procedure (PTP) code pair edits are automated prepayment...
Medical Billing Audit Unlocks $20K in Claims After Cyberattack

Medical Billing Audit Unlocks $20K in Claims After Cyberattack

by Alex Mitchell | Sep 15, 2025 | Tips for New Lab Owners, Denial Management, Case Studies, Payer Audits & Alerts, Revenue Cycle Management, Industry Insights

00:00 1X   As we look back at recent trends, 2024 may go down as the year of the cyberattack. In February of last year, the Change Healthcare breach made national headlines as the largest healthcare cyberattack in history, halting claims submission and disrupting...
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